Clinical Trials

Bioequivalence study of Empagliflozin 25 mg Tablet

Principal Investigator: Urmi Lohani Lead Clinical Researcher

CRO: M/S. Novas Clinical Research Services Ltd. (NCRSL),

Application Date: 26 May, 2022

Performance evaluation of a multiplex BRiCM RT-PCR kit for the detection of SARSCoV- 2

Principal Investigator: Mamudul Hasan Razu Scientific Officer Bangladesh Reference Institute for Chemical Measurements (BRiCM) Dr. Qudrat-e-Khuda Road (Laboratory Road) Dhanmondi, Dhaka-1205

CRO: Institute for developing science and health initiatives (ideSHi),

Application Date: 25 May, 2022

A Phase 3 Study to Evaluate Zimberelimab (AB122) Monotherapy Compared to Standard Chemotherapy or Zimberelimab Combined with AB154 in Front-Line, PD-L1-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Principal Investigator: Dr. Zhahirul Islam, PhD Principal Investigator (icddr,b) ARC-10 study Scientist, Laboratory Sciences and Services Division icddr,b. Phone no. +8801710957036 Email: zislam@icddrb.org

CRO: International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b).

Application Date: 16 May, 2022

Clinical trial to determine and validate the effectiveness of a locally developed diagnostic kit (BCS IR-COVID Kit) for the detection of SARS-CoV-2

Principal Investigator: Professor Dr. Md. Aftab Ali Shaikh Principal Investigator & Chairman, BCSIR

CRO: Bangladesh Council of Scientific & clinical research (BCSIR)

Application Date: 27 Apr, 2022

Methotrexate & Prednisolone study in Erythima Nodosam loprosam

Principal Investigator: Dr. Samsun Nahar Residential Medical Officer Danish bangladesh Laprosy Mission Hospital,

CRO: Leprosy Mission International

Application Date: 28 Mar, 2022

Acceptability and Efficacy of Entered (VS001) in Children at Risk for Environmental Enteric Dysfunction in Bangladesh

Principal Investigator: Dr. Masud Alam Enteric and Respiratory Infections Programme, Infectious Research Division, icddr,b

CRO: International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b).

Application Date: 2 Feb, 2022

The WHO Antenatal Corticosteroids for Improving Outcomes in Preterm Newborns (ACTION) TrialsACTIONS III: A multicountry, multi-center, threearm, parallel group, doubleblind, placebo-controlled, randomized trial of two doses of antenatal corticosteroids for women with a high probability of birth in the late preterm period in hospitals in lowresource countries to improve newborn outcomes.

Principal Investigator: 1.Prof. Dr. Mohammod Shahidullah, Professor, Neonatology Department, Bangabandhu Sheikh Mujib Medical University (BSMMU) 2.Prof. Dr. Saleha Begum Chowdhury, Professor, Department of Obstetrics and Gynecology.

CRO: M/S Projahnmo Research Foundation

Application Date: 26 Jan, 2022

Clinical Trial to compare the efficacy and safety of a multiple amino-acid based ORS “VS002A” with the standard WHO-ORS in the management of non-cholera acute watery diarrhoea in infants and young children.

Principal Investigator: Dr. Tahmeed Ahmed, Investigator and Senior Director, Nutrition and Clinical Services Division, icddr.b

CRO: International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b).

Application Date: 12 Dec, 2021

Azithromycin & cefixime combination Verses azithromycin alone for the outpatient treatment of clinically suspected or confirmed uncomplicated Typhoid fever in South Asia: a randomized controlled trial (The ACT South Asia Trial)

Principal Investigator: Dr. Md. Shabab Hossain, Assistant Scientist, Nutrition & clinical Services Division, icddr,b

CRO: International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b).

Application Date: 9 Dec, 2021

“A double-blind randomized, controlled, non-inferiority trial to evaluate the immunogenicity and safety of new Rabies Vaccine ‘RabixVC’ on Bangladesh healthy adults”.

Principal Investigator: Dr. Taufiqur Rahman Bhuiyan Principal Investigator of Research Protocol# PR20117 Infectious Diseases Division (IDD), icddr,b

CRO: International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b).

Application Date: 1 Dec, 2021

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